Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NQO1 | P15559 | 1/20 | 0.33 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9025560 | 0.82 | METAP2 (0.40) | TSHRMAPTSMN1; SMN2ALDH1A1NQO1 | |
| SCHEMBL9025513 | 0.81 | ALDH1A1 (0.50) | TSHRMAPTTP53ALDH1A1NQO1 | |
| SCHEMBL9025535 | 0.80 | SHMT2 (0.31) | SHMT2HTR6 | |
| SCHEMBL9026853 | 0.79 | GAA (0.45) | TSHRMAPTSMN1; SMN2ALDH1A1NQO1 | |
| SCHEMBL9216015 | 0.78 | NQO1 (0.37) | TSHRMAPTALDH1A1NQO1EGFR | |
| SCHEMBL9026004 | 0.78 | NQO1 (0.37) | TSHRMAPTALDH1A1NQO1HTR2A | |
| SCHEMBL9024891 | 0.78 | NQO1 (0.37) | TSHRMAPTSMN1; SMN2ALDH1A1NQO1 | |
| SCHEMBL9025087 | 0.78 | ALDH1A1 (0.39) | GLATSHRMAPTTP53SMN1; SMN2 | |
| SCHEMBL9025461 | 0.76 | TP53 (0.35) | TSHRMAPTTP53ALDH1A1MEN1 | |
| SCHEMBL9026007 | 0.76 | RAB9A (0.35) | TSHRMAPTTP53SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711290-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995004052-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1995-02-09 | — | — | WO | disclosed |