Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.35 |
| ▸ | MAP2 | P11137 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TSPO | P30536 | 1/20 | 0.31 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9026841 | 0.90 | SHMT2 (0.37) | SLC9A1SHMT2MEN1NPC1POLB | |
| SCHEMBL9026425 | 0.87 | TSHR (0.35) | SLC9A1CYP1A2MAPTCYP2C9CYP2C19 | |
| SCHEMBL9025860 | 0.84 | MAOA (0.32) | — | |
| SCHEMBL9025563 | 0.84 | GRM2 (0.32) | MAPTMEN1KMT2A | |
| SCHEMBL9025844 | 0.82 | ACLY (0.35) | SLC9A1MAPTSHMT2MEN1NPC1 | |
| SCHEMBL9032006 | 0.82 | CYP1A2 (0.36) | SLC9A1MAP2IRAK4CYP1A2MAPT | |
| SCHEMBL9025570 | 0.81 | CCR2 (0.31) | — | |
| SCHEMBL9026248 | 0.81 | TSHR (0.39) | SLC9A1CYP1A2MAPTMEN1NPC1 | |
| SCHEMBL9026385 | 0.80 | CRHR1 (0.35) | SLC9A1SHMT2MEN1NPC1POLB | |
| SCHEMBL9026539 | 0.78 | SLC9A1 (0.37) | SLC9A1MAP2IRAK4CYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711290-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995004052-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1995-02-09 | — | — | WO | disclosed |