Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NQO1 | P15559 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | CASP9 | P55211 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9026462 | 0.90 | LTA4H (0.40) | GAATSHRNQO1DHFRMAPT | |
| SCHEMBL9025513 | 0.87 | ALDH1A1 (0.50) | GAATSHRNQO1MAPTALDH1A1 | |
| SCHEMBL9216015 | 0.86 | NQO1 (0.37) | GAATSHRNQO1DHFRMAPT | |
| SCHEMBL9024891 | 0.86 | NQO1 (0.37) | GAATSHRNQO1MAPTAPAF1 | |
| SCHEMBL9025560 | 0.86 | METAP2 (0.40) | TSHRNQO1MAPTALDH1A1MEN1 | |
| SCHEMBL9026004 | 0.86 | NQO1 (0.37) | GAATSHRNQO1DHFRMAPT | |
| SCHEMBL9025087 | 0.86 | ALDH1A1 (0.39) | GAATSHRNQO1MAPTALDH1A1 | |
| SCHEMBL9032013 | 0.81 | MAPT (0.37) | GAATSHRNQO1MAPTALDH1A1 | |
| SCHEMBL9025426 | 0.80 | ALDH1A1 (0.42) | GAATSHRALDH1A1MEN1KMT2A | |
| SCHEMBL9026126 | 0.80 | HRH3 (0.48) | MAPTALDH1A1KMT2AKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711290-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995004052-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1995-02-09 | — | — | WO | disclosed |