Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | NQO1 | P15559 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9026853 | 0.87 | GAA (0.45) | ALDH1A1MAPTLMNANQO1GAA | |
| SCHEMBL9216015 | 0.86 | NQO1 (0.37) | ALDH1A1MAPTNQO1GAAACHE | |
| SCHEMBL9026004 | 0.86 | NQO1 (0.37) | ALDH1A1MAPTNQO1GAAACHE | |
| SCHEMBL9024891 | 0.86 | NQO1 (0.37) | ALDH1A1MAPTNQO1GAAACHE | |
| SCHEMBL9025087 | 0.86 | ALDH1A1 (0.39) | ALDH1A1MAPTLMNATP53NQO1 | |
| SCHEMBL9025560 | 0.86 | METAP2 (0.40) | ALDH1A1MAPTMETAP2NQO1ACHE | |
| SCHEMBL9026462 | 0.83 | LTA4H (0.40) | ALDH1A1MAPTLMNANQO1GAA | |
| SCHEMBL9026655 | 0.81 | GLA (0.36) | ALDH1A1MAPTTP53NQO1KMT2A | |
| SCHEMBL9025279 | 0.81 | MAPT (0.44) | ALDH1A1MAPTLMNAGAAACHE | |
| SCHEMBL9032013 | 0.81 | MAPT (0.37) | ALDH1A1MAPTLMNATP53NQO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711290-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995004052-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1995-02-09 | — | — | WO | disclosed |