Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15278202 | 0.79 | ALDH1A1 (0.50) | TBXAS1ALDH1A1 | |
| SCHEMBL9029370 | 0.76 | TBXAS1 (0.54) | TBXAS1KDM4EALDH1A1 | |
| SCHEMBL9029379 | 0.76 | TBXAS1 (0.61) | TBXAS1KDM4EALDH1A1 | |
| SCHEMBL9030109 | 0.76 | CHRM1 (0.51) | TBXAS1KDM4EALDH1A1 | |
| SCHEMBL10852854 | 0.76 | SMN1; SMN2 (0.58) | KDM4EALDH1A1 | |
| SCHEMBL4399230 | 0.76 | ALDH1A1 (0.54) | TBXAS1ALDH1A1 | |
| SCHEMBL49130 | 0.73 | L3MBTL1 (0.66) | ALDH1A1 | |
| SCHEMBL11358034 | 0.73 | TBXAS1 (0.64) | TBXAS1KDM4EALDH1A1 | |
| SCHEMBL17482346 | 0.72 | L3MBTL1 (0.60) | TBXAS1ALDH1A1 | |
| SCHEMBL11287668 | 0.72 | TBXAS1 (0.71) | TBXAS1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0426714-B1 | ACETYLENIC IMIDAZOLES HAVING CENTRAL NERVOUS SYSTEM ACTIVITY | UPJOHN CO (US) | 1996-04-03 | — | — | EP | claimed |
| EP-0426714-B1 | ACETYLENIC IMIDAZOLES HAVING CENTRAL NERVOUS SYSTEM ACTIVITY | UPJOHN CO (US) | 1996-04-03 | — | — | EP | disclosed |
| US-5100909-A | Cholinergic antagonists, analgesics, treatment of Alzheimer*s disease | THE UPJOHN COMPANY (US) | 1992-03-31 | — | — | US | disclosed |
| EP-0426714-A1 | ACETYLENIC IMIDAZOLES HAVING CENTRAL NERVOUS SYSTEM ACTIVITY. | UPJOHN CO (US) | 1991-05-15 | — | — | EP | disclosed |
| WO-1990001026-A1 | ACETYLENIC IMIDAZOLES HAVING CENTRAL NERVOUS SYSTEM ACTIVITY | THE UPJOHN COMPANY (US) | 1990-02-08 | — | — | WO | disclosed |