Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 2/20 | 0.41 |
| ▸ | GLP1R | P43220 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9030188 | 1.00 | P2RY2 (0.41) | P2RY2GLP1RKDM4EALDH1A1POLB | |
| SCHEMBL5668664 | 0.84 | TK1 (0.39) | — | |
| SCHEMBL6851558 | 0.83 | TK1 (0.34) | — | |
| SCHEMBL8539644 | 0.81 | LMNA (0.37) | P2RY2SMN1; SMN2 | |
| SCHEMBL8004041 | 0.73 | LMNA (0.42) | ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL9030185 | 0.72 | P2RY2 (0.51) | P2RY2 | |
| SCHEMBL9029499 | 0.72 | P2RY2 (0.51) | P2RY2 | |
| SCHEMBL6468417 | 0.71 | PNP (0.41) | — | |
| SCHEMBL27928944 | 0.71 | P2RY2 (0.41) | P2RY2SMN1; SMN2 | |
| SCHEMBL8469095 | 0.69 | RNASE1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0357571-B1 | Pyrimidine nucleosides | MEDIVIR AB (SE) | 1996-04-03 | — | — | EP | disclosed |
| EP-0691333-A2 | Pyrimidine derivatives, process for their preparation and their use as precursors | Medivir Aktiebolag (SE) | 1996-01-10 | — | — | EP | disclosed |
| EP-0357571-A2 | Pyrimidine nucleosides | Medivir Aktiebolag (SE) | 1990-03-07 | — | — | EP | disclosed |