Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 6/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9025568 | 0.79 | METAP2 (0.39) | KDM4ENPC1RAB9AALDH1A1ACHE | |
| SCHEMBL9025904 | 0.78 | — | — | |
| SCHEMBL9026660 | 0.77 | MAPT (0.35) | KDM4EALDH1A1LMNAGLASMN1; SMN2 | |
| SCHEMBL9026859 | 0.74 | ADRA2A (0.45) | CYP1A2KDM4ENPC1RAB9ACYP2A6 | |
| SCHEMBL9025520 | 0.74 | METAP2 (0.38) | KDM4ECYP3A4ALDH1A1LMNAACHE | |
| SCHEMBL9025089 | 0.74 | KDM4E (0.41) | KDM4ENPC1RAB9ACYP3A4ALDH1A1 | |
| SCHEMBL9216019 | 0.73 | NQO1 (0.36) | BCHEACHE | |
| SCHEMBL9025454 | 0.73 | CA12 (0.34) | CYP1A2KDM4ECYP2A6CYP2D6ALDH1A1 | |
| SCHEMBL9024896 | 0.73 | MYB (0.36) | NPC1RAB9ALMNAACHEMEN1 | |
| SCHEMBL9026008 | 0.73 | PKM (0.38) | PKMACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711290-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1996-05-15 | — | — | EP | disclosed |