Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | TNF | P01375 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9032737 | 0.88 | CTSL (0.44) | RAB9ALMNACAPN1 | |
| SCHEMBL9031818 | 0.87 | CTSL (0.44) | RAB9ACAPN1 | |
| SCHEMBL9034601 | 0.85 | CTSL (0.40) | MEN1KMT2ARAB9ALMNACAPN1 | |
| SCHEMBL9033094 | 0.79 | ITGB3 (0.45) | NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL9033818 | 0.78 | CTSL (0.45) | MAPTLMNACAPN1 | |
| SCHEMBL9033091 | 0.77 | CTSL (0.46) | MAPTLMNACAPN1 | |
| SCHEMBL8697846 | 0.74 | OPRK1 (0.44) | LMNATSHR | |
| SCHEMBL9033877 | 0.74 | SMN1; SMN2 (0.44) | MEN1KMT2AL3MBTL1MAPTKDM4E | |
| SCHEMBL9034272 | 0.74 | ATM (0.45) | LMNAALDH1A1TSHR | |
| SCHEMBL9034257 | 0.74 | SMN1; SMN2 (0.41) | POLBMEN1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696586-A1 | SERINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |