Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | G6PD | P11413 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TPMT | P51580 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20285973 | 0.87 | GPR35 (0.44) | MAPTMAPK1KDM4EMEN1KMT2A | |
| SCHEMBL1734996 | 0.86 | TDP1 (0.45) | MAPTMAPK1KDM4EMEN1G6PD | |
| SCHEMBL2402093 | 0.84 | GPR35 (0.61) | MAPTMAPK1KDM4EMEN1G6PD | |
| SCHEMBL19341723 | 0.83 | MAPT (0.45) | MAPTMAPK1KDM4EMEN1G6PD | |
| SCHEMBL12648406 | 0.80 | ESR1 (0.49) | MAPTMAPK1KMT2AAKR1C3AKR1C2 | |
| SCHEMBL15199259 | 0.80 | GPR35 (0.56) | MAPTMAPK1KDM4EMEN1G6PD | |
| SCHEMBL12326834 | 0.79 | ALDH1A1 (0.53) | MAPTMAPK1KDM4EAKR1C3AKR1C2 | |
| SCHEMBL1632528 | 0.79 | ALDH1A1 (0.57) | MAPTMAPK1KDM4EMEN1KMT2A | |
| SCHEMBL29189968 | 0.78 | MEN1 (0.50) | MAPTMAPK1KDM4EMEN1KMT2A | |
| SCHEMBL31392530 | 0.78 | GPR35 (0.69) | MAPTMAPK1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170260149-A1 | A Process for Preparing Olodaterol and Intermediates Thereof | REDDY, G. Pratap (IN) | 2017-09-14 | — | — | US | disclosed |
| US-8420809-B2 | Process for the manufacturing of betamimetics | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-04-16 | — | — | US | disclosed |
| US-20110124859-A1 | PROCESS FOR THE MANUFACTURING OF BETAMIMETICS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-05-26 | — | — | US | disclosed |
| US-20070088160-A1 | PROCESS FOR THE MANUFACTURING OF BETAMIMETICS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-04-19 | — | — | US | disclosed |
| EP-0485984-B1 | Diarylmethoxypiperidine derivatives | UBE INDUSTRIES (JP) | 1996-04-24 | — | — | EP | disclosed |
| US-5225559-A | DIARYLMETHOXYPIPERIDINE DERIVATIVES | UBE INDUSTRIES, LTD. (JP) | 1993-07-06 | — | — | US | disclosed |
| EP-0485984-A2 | Diarylmethoxypiperidine derivatives | UBE INDUSTRIES, LTD. (JP) | 1992-05-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170260149-A1 | A Process for Preparing Olodaterol and Intermediates Thereof | CYP4A11, CYP11B1, CYP11B2 | MAPT 4331/4885MAPK1 503/4885KDM4E 2763/4885 |
| US-20070088160-A1 | PROCESS FOR THE MANUFACTURING OF BETAMIMETICS | ADRA1D, ADRB1, ADRA1A | MAPT 3603/4885MAPK1 1741/4885KDM4E 1849/4885 |
| US-20110124859-A1 | PROCESS FOR THE MANUFACTURING OF BETAMIMETICS | ADRA1D, ADRB1, ADRA1A | MAPT 3603/4885MAPK1 1741/4885KDM4E 1849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.