Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 4/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.43 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.43 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 3/20 | 0.42 |
| ▸ | CTSB | P07858 | 2/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9031818 | 0.85 | CTSL (0.44) | OPRK1BCHEACHECACNA1FCACNA1D | |
| SCHEMBL9032737 | 0.84 | CTSL (0.44) | OPRK1BCHEACHECACNA1FCACNA1D | |
| SCHEMBL9033094 | 0.79 | ITGB3 (0.45) | OPRK1CTSLCTSBCTSKITGB3 | |
| SCHEMBL9032558 | 0.79 | HTT (0.45) | OPRK1BCHEACHECACNA1FCACNA1D | |
| SCHEMBL9033091 | 0.75 | CTSL (0.46) | OPRK1CTSLCTSBCTSKITGB3 | |
| SCHEMBL9034601 | 0.74 | CTSL (0.40) | BCHEACHECACNA1FCACNA1DCACNA1S | |
| SCHEMBL9033818 | 0.74 | CTSL (0.45) | OPRK1CTSLCTSBCTSKITGB3 | |
| SCHEMBL9033877 | 0.74 | SMN1; SMN2 (0.44) | OPRK1CYP2D6CYP2C9MEN1LMNA | |
| SCHEMBL9033382 | 0.73 | CTSL (0.43) | OPRK1BCHEACHECACNA1FCACNA1D | |
| SCHEMBL9033014 | 0.73 | POLB (0.42) | RAB9AMEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696586-A1 | SERINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |