Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 4/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9033650 | 0.87 | KDM4E (0.47) | HTR7HTR2AHTR1ASLC6A4 | |
| SCHEMBL9034191 | 0.84 | DRD2 (0.57) | HTR7HTR2AHTR1ASLC6A4ADRA1D | |
| SCHEMBL9035549 | 0.84 | HTR1A (0.59) | HTR7HTR2AHTR1ASLC6A4 | |
| SCHEMBL9033100 | 0.78 | TDP1 (0.43) | HTR7HTR2AHTR1ASLC6A4TDP1 | |
| SCHEMBL8878576 | 0.77 | SLC6A4 (0.55) | HTR2AHTR1ASLC6A4ADRA1D | |
| SCHEMBL9034861 | 0.76 | KDM4E (0.47) | HTR7HTR2AHTR1A | |
| SCHEMBL9035214 | 0.76 | MEN1 (0.47) | HTR7HTR2AHTR1ASLC6A4 | |
| SCHEMBL8879463 | 0.75 | SLC6A4 (0.62) | HTR1ASLC6A4ADRA1D | |
| SCHEMBL5380517 | 0.74 | HTR1F (0.48) | HTR7HTR2AHTR1ASLC6A4ADRA1D | |
| SCHEMBL9033610 | 0.74 | MEN1 (0.45) | HTR7HTR2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722942-A1 | Indole piperidine derivatives | MERCK PATENT GmbH (DE) | 1996-07-24 | — | — | EP | disclosed |