Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9035725 | 0.86 | HTR2C (0.33) | HTR2CHTR2A | |
| SCHEMBL9035491 | 0.81 | SLC6A2 (0.33) | HTR2CHTR2A | |
| SCHEMBL9035829 | 0.79 | HTR2C (0.34) | HTR2CHTR2ANFKB1NFKB2RELA | |
| SCHEMBL9035449 | 0.73 | NFKB1 (0.41) | NFKB1NFKB2RELA | |
| SCHEMBL4625971 | 0.69 | HTR2C (0.36) | HTR2CHTR2A | |
| SCHEMBL29756154 | 0.69 | HTR2C (0.34) | HTR2CHTR2ANFKB1NFKB2RELA | |
| SCHEMBL4538261 | 0.69 | HTR2C (0.34) | HTR2CHTR2ANFKB1NFKB2RELA | |
| SCHEMBL8681014 | 0.67 | ALDH1A1 (0.39) | HTR2CHTR2A | |
| SCHEMBL9917550 | 0.64 | HSD17B10 (0.43) | — | |
| SCHEMBL15196167 | 0.64 | ALDH1A1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540690-B1 | PHOTOCHROMIC CHROMENE COMPOUNDS | PPG INDUSTRIES INC (US) | 1996-05-29 | — | — | EP | disclosed |
| EP-0540690-A1 | PHOTOCHROMIC CHROMENE COMPOUNDS. | PPG INDUSTRIES INC (US) | 1993-05-12 | — | — | EP | disclosed |
| US-5200116-A | Which experience a reversible change from colorless to orange upon exposure to sunlight | PPG INDUSTRIES, INC. (US) | 1993-04-06 | — | — | US | disclosed |
| EP-0540690-A4 | PHOTOCHROMIC CHROMENE COMPOUNDS. | PPG INDUSTRIES INC (US) | 1993-02-12 | — | — | EP | disclosed |
| WO-1992001959-A1 | PHOTOCHROMIC CHROMENE COMPOUNDS | PPG INDUSTRIES, INC. (US) | 1992-02-06 | — | — | WO | disclosed |