Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.41 |
| ▸ | RELA | Q04206 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MYB | P10242 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 3/20 | 0.35 |
| ▸ | EDNRB | P24530 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.32 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.32 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9035829 | 0.87 | HTR2C (0.34) | NFKB1NFKB2RELA | |
| SCHEMBL1844408 | 0.81 | NFKB1 (0.37) | NFKB1NFKB2RELAKMT2AEDNRA | |
| SCHEMBL7529018 | 0.81 | RAB9A (0.37) | NFKB1NFKB2RELAKMT2AMYB | |
| SCHEMBL8978539 | 0.77 | MYB (0.34) | NFKB1NFKB2RELAKMT2AMYB | |
| SCHEMBL9035491 | 0.74 | SLC6A2 (0.33) | KMT2ASLC6A4CHRM2MAPTSLC6A2 | |
| SCHEMBL9035611 | 0.73 | HTR2C (0.31) | NFKB1NFKB2RELA | |
| SCHEMBL12152336 | 0.70 | NFKB1 (0.50) | NFKB1NFKB2RELAKMT2AMYB | |
| SCHEMBL4625971 | 0.69 | HTR2C (0.36) | KMT2ACYP1A1CYP1A2CYP1B1SLC6A4 | |
| SCHEMBL4538261 | 0.69 | HTR2C (0.34) | NFKB1NFKB2RELA | |
| SCHEMBL29756154 | 0.69 | HTR2C (0.34) | NFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540690-B1 | PHOTOCHROMIC CHROMENE COMPOUNDS | PPG INDUSTRIES INC (US) | 1996-05-29 | — | — | EP | disclosed |
| EP-0540690-A1 | PHOTOCHROMIC CHROMENE COMPOUNDS. | PPG INDUSTRIES INC (US) | 1993-05-12 | — | — | EP | disclosed |
| US-5200116-A | Which experience a reversible change from colorless to orange upon exposure to sunlight | PPG INDUSTRIES, INC. (US) | 1993-04-06 | — | — | US | disclosed |
| EP-0540690-A4 | PHOTOCHROMIC CHROMENE COMPOUNDS. | PPG INDUSTRIES INC (US) | 1993-02-12 | — | — | EP | disclosed |
| WO-1992001959-A1 | PHOTOCHROMIC CHROMENE COMPOUNDS | PPG INDUSTRIES, INC. (US) | 1992-02-06 | — | — | WO | disclosed |