Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.66 |
| ▸ | MITF | O75030 | 5/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.66 |
| ▸ | HTT | P42858 | 4/20 | 0.66 |
| ▸ | ATM | Q13315 | 3/20 | 0.66 |
| ▸ | RAB9A | P51151 | 3/20 | 0.66 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.66 |
| ▸ | GFER | P55789 | 1/20 | 0.66 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 10/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | TP53 | P04637 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9034949 | 0.84 | ALDH1A1 (0.60) | SMN1; SMN2MITFALDH1A1HTTATM | |
| SCHEMBL6325548 | 0.81 | SMN1; SMN2 (0.97) | SMN1; SMN2MITFALDH1A1HTTATM | |
| SCHEMBL6321267 | 0.80 | SMN1; SMN2 (0.94) | SMN1; SMN2MITFALDH1A1HTTATM | |
| SCHEMBL9035306 | 0.78 | DPP4 (0.47) | SMN1; SMN2MITFALDH1A1HTTATM | |
| SCHEMBL6320116 | 0.77 | SMN1; SMN2 (0.81) | SMN1; SMN2MITFALDH1A1HTTATM | |
| SCHEMBL9036691 | 0.73 | ALDH1A1 (0.55) | SMN1; SMN2ALDH1A1RAB9AGFERLMNA | |
| SCHEMBL9037029 | 0.71 | CHRM2 (0.50) | ALDH1A1NTSR1LMNAHSP90AA1L3MBTL1 | |
| SCHEMBL10852952 | 0.71 | SMN1; SMN2 (0.77) | SMN1; SMN2MITFALDH1A1HTTATM | |
| SCHEMBL9035245 | 0.71 | KMT2A (0.62) | ALDH1A1GFERLMNAMAPTKMT2A | |
| SCHEMBL7580361 | 0.69 | L3MBTL1 (0.59) | SMN1; SMN2MITFALDH1A1HTTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411775-B1 | Heterocyclic compounds containing nitrogen and sulfur, processes for their preparation and pharmaceutical compositions thereof | RICHTER GEDEON VEGYESZET (HU) | 1996-03-13 | — | — | EP | disclosed |
| US-5096902-A | Cerebral antihypoxic action, senile dememtia, Alzheimer's, cognitive functions | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1992-03-17 | — | — | US | disclosed |
| EP-0411775-A1 | Heterocyclic compounds containing nitrogen and sulfur, processes for their preparation and pharmaceutical compositions thereof | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1991-02-06 | — | — | EP | disclosed |