Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CPA1 | P15085 | 2/20 | 0.38 |
| ▸ | CPA3 | P15088 | 2/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9034949 | 0.80 | ALDH1A1 (0.60) | DPP4RAB9AALDH1A1HTTATM | |
| SCHEMBL9036951 | 0.78 | SMN1; SMN2 (0.66) | DPP4RAB9AALDH1A1HTTATM | |
| SCHEMBL6202028 | 0.78 | ALDH1A1 (0.75) | RAB9AALDH1A1HTTATMLMNA | |
| SCHEMBL6201853 | 0.74 | MDM2 (0.70) | RAB9AHTTATMMAPTMDM2 | |
| SCHEMBL9036691 | 0.71 | ALDH1A1 (0.55) | RAB9AALDH1A1LMNAMAPTGFER | |
| SCHEMBL9035245 | 0.69 | KMT2A (0.62) | ALDH1A1LMNAMAPTGFER | |
| SCHEMBL2075836 | 0.68 | SIGMAR1 (0.59) | ALDH1A1LMNA | |
| SCHEMBL9037029 | 0.67 | CHRM2 (0.50) | ALDH1A1LMNA | |
| SCHEMBL14068950 | 0.66 | ALDH1A1 (0.60) | RAB9AALDH1A1HTTATMLMNA | |
| SCHEMBL7718161 | 0.66 | ALDH1A1 (0.60) | RAB9AALDH1A1HTTATMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411775-B1 | Heterocyclic compounds containing nitrogen and sulfur, processes for their preparation and pharmaceutical compositions thereof | RICHTER GEDEON VEGYESZET (HU) | 1996-03-13 | — | — | EP | disclosed |
| US-5096902-A | Cerebral antihypoxic action, senile dememtia, Alzheimer's, cognitive functions | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1992-03-17 | — | — | US | disclosed |
| EP-0411775-A1 | Heterocyclic compounds containing nitrogen and sulfur, processes for their preparation and pharmaceutical compositions thereof | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1991-02-06 | — | — | EP | disclosed |