Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8444881 | 0.87 | GRIN2B (0.36) | CCR5GRIN2BALDH1A1HTTMAPT | |
| SCHEMBL9120984 | 0.86 | OPRK1 (0.39) | KMT2ANPBWR1MCHR1ALDH1A1 | |
| SCHEMBL6939249 | 0.86 | KMT2A (0.41) | CCR5KMT2ANPBWR1MCHR1ALDH1A1 | |
| SCHEMBL8447213 | 0.86 | GRIN2B (0.37) | CCR5KMT2AGRIN2BALDH1A1HTT | |
| SCHEMBL7450103 | 0.86 | GRIN2B (0.37) | CCR5KMT2AGRIN2BALDH1A1HTT | |
| SCHEMBL9728223 | 0.85 | DPP8 (0.46) | NPBWR1MCHR1 | |
| SCHEMBL9040592 | 0.85 | ALDH1A1 (0.41) | KMT2ANPBWR1MCHR1ALDH1A1MAPT | |
| SCHEMBL9040433 | 0.85 | ALDH1A1 (0.41) | KMT2ANPBWR1MCHR1ALDH1A1MAPT | |
| SCHEMBL9119637 | 0.84 | DPP8 (0.45) | KMT2ANPBWR1MCHR1ALDH1A1MAPT | |
| SCHEMBL8449152 | 0.84 | CCR5 (0.36) | CCR5GRIN2BALDH1A1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0442497-B1 | Novel beta-lactam compounds and their production | SUMITOMO PHARMA (JP) | 1996-08-14 | — | — | EP | disclosed |
| US-5227376-A | Quaternary ammonium carbapenem antibiotics | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1993-07-13 | — | — | US | disclosed |
| EP-0442497-A1 | Novel beta-lactam compounds and their production | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-08-21 | — | — | EP | disclosed |