Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOX | P28300 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10133871 | 0.78 | NOS3 (0.43) | LOXGPR119MBOAT4KDM4EALDH1A1 | |
| SCHEMBL945673 | 0.75 | G6PD (0.36) | LOXGPR119MBOAT4KDM4EALDH1A1 | |
| SCHEMBL13076453 | 0.75 | GPR119 (0.32) | LOXGPR119MBOAT4KDM4EALDH1A1 | |
| SCHEMBL27935105 | 0.75 | GPR119 (0.32) | LOXGPR119MBOAT4KDM4EALDH1A1 | |
| SCHEMBL541733 | 0.75 | ENPP2 (0.35) | LOXGPR119MBOAT4KDM4EALDH1A1 | |
| SCHEMBL2334782 | 0.75 | RAB9A (0.35) | LOXGPR119MBOAT4KDM4EALDH1A1 | |
| SCHEMBL3792466 | 0.75 | LOX (0.41) | LOXGPR119MBOAT4KDM4EALDH1A1 | |
| SCHEMBL10116156 | 0.72 | GPR119 (0.36) | GPR119ALDH1A1 | |
| SCHEMBL19454534 | 0.72 | GAA (0.34) | GPR119KDM4EALDH1A1GAA | |
| SCHEMBL2616448 | 0.72 | ALDH1A1 (0.34) | GPR119ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012041158-A1 | TRICYCLIC COMPOUND, PREPARATION METHOD AND PHARMACEUTICAL USE THEREOF | 上海恒瑞医药有限公司 (CN) | 2012-04-05 | — | — | WO | disclosed |