Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 1/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 8/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9053116 | 0.79 | HPGD (0.40) | ACKR3HPGD | |
| SCHEMBL9044008 | 0.77 | DPP4 (0.48) | VNN1HPGDADORA2BADORA2AHDAC4 | |
| SCHEMBL3723757 | 0.73 | VNN1 (0.40) | VNN1HPGDADORA2BADORA2AADORA3 | |
| SCHEMBL17350579 | 0.73 | HSD11B1 (0.48) | VNN1HPGDHDAC4 | |
| SCHEMBL29688509 | 0.68 | L3MBTL1 (0.66) | VNN1 | |
| SCHEMBL7381076 | 0.68 | L3MBTL1 (0.66) | VNN1 | |
| SCHEMBL3528247 | 0.67 | NUDT1 (0.45) | ADORA3 | |
| SCHEMBL34463038 | 0.66 | PDK2 (0.49) | VNN1HPGDADORA2BHDAC4 | |
| SCHEMBL21212226 | 0.66 | PROKR1 (0.62) | VNN1HPGD | |
| SCHEMBL34462951 | 0.66 | PDK2 (0.49) | VNN1HPGDADORA2BHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743944-A1 | AZACYCLIC DERIVATIVES | SmithKline Beecham Farmaceutici S.p.A. (IT) | 1996-11-27 | — | — | EP | disclosed |
| WO-1995021843-A1 | AZACYCLIC DERIVATIVES | SMITHKLINE BEECHAM FARMACEUTICI S.P.A. (IT) | 1995-08-17 | — | — | WO | disclosed |