Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 8/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9046781 | 0.84 | LIPE (0.45) | LIPEMAPTALDH1A1HTTHSPB1 | |
| SCHEMBL27315098 | 0.84 | LIPE (0.45) | LIPEMAPTALDH1A1HTTHSPB1 | |
| SCHEMBL7753213 | 0.80 | MAPT (0.39) | MAPTALDH1A1HTTKMT2AL3MBTL1 | |
| SCHEMBL10440281 | 0.80 | MAPT (0.39) | MAPTALDH1A1HTTKMT2AL3MBTL1 | |
| SCHEMBL27316025 | 0.77 | LIPE (0.41) | LIPEMAPTHSPB1HRH3RAB9A | |
| SCHEMBL9046364 | 0.75 | ALDH1A1 (0.36) | MAPTALDH1A1HTTKMT2A | |
| SCHEMBL27316024 | 0.74 | LIPE (0.45) | LIPEMAPTALDH1A1HTTHSPB1 | |
| SCHEMBL9044324 | 0.74 | MAPT (0.48) | LIPEMAPTALDH1A1HTTDAGLA | |
| SCHEMBL9046783 | 0.68 | OPRM1 (0.40) | MAPTALDH1A1HSPB1KMT2ADAGLA | |
| SCHEMBL11274403 | 0.68 | HSPB1 (0.73) | MAPTALDH1A1HTTHSPB1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366085-B1 | Tetrahydropyrimidines, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-04-17 | — | — | EP | disclosed |
| US-5084459-A | Insecticides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-01-28 | — | — | US | disclosed |