Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CRHBP | P24387 | 2/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7684819 | 0.82 | CRHR1 (0.40) | SLC2A1ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL12485504 | 0.67 | AURKA (0.44) | SLC2A1ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL9048746 | 0.64 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL3406616 | 0.64 | KDM4E (0.44) | ALDH1A1MEN1KMT2ATSHRCRHBP | |
| SCHEMBL9044173 | 0.63 | CRHR1 (0.46) | ALDH1A1MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL7682687 | 0.61 | CRHR1 (0.62) | CRHR1 | |
| SCHEMBL11013373 | 0.61 | HRH4 (0.42) | HRH3 | |
| SCHEMBL12485322 | 0.60 | AURKA (0.53) | SLC2A1ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL20042146 | 0.60 | MAPT (0.65) | SLC2A1ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL12484199 | 0.60 | MEN1 (0.63) | SLC2A1ALDH1A1MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0723533-A1 | 1N-ALKYL-N-ARYLPYRIMIDINAMINES AND DERIVATIVES THEREOF | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-07-31 | — | — | EP | disclosed |