Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | ALPG | P10696 | 1/20 | 0.37 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9047601 | 0.86 | MAPT (0.41) | ALDH1A1MAPTRAB9ANPC1MEN1 | |
| SCHEMBL9049433 | 0.85 | MAPT (0.39) | ALDH1A1MAPTRAB9ANPC1MEN1 | |
| SCHEMBL9046694 | 0.83 | ALDH1A1 (0.40) | ALDH1A1MAPTRAB9ANPC1MEN1 | |
| SCHEMBL7684971 | 0.78 | MAPT (0.67) | ALDH1A1MAPTRAB9ANPC1MEN1 | |
| SCHEMBL7678043 | 0.73 | MAPT (0.59) | ALDH1A1MAPTRAB9ANPC1MEN1 | |
| SCHEMBL9047853 | 0.70 | CRHR1 (0.46) | — | |
| SCHEMBL9047025 | 0.69 | CRHR1 (0.65) | — | |
| SCHEMBL20918900 | 0.68 | SKP2 (0.46) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL20048186 | 0.68 | SKP2 (0.50) | ALDH1A1RAB9AKMT2A | |
| SCHEMBL21677170 | 0.67 | CNR1 (0.48) | THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0723533-A1 | 1N-ALKYL-N-ARYLPYRIMIDINAMINES AND DERIVATIVES THEREOF | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-07-31 | — | — | EP | disclosed |