SCHEMBL904515

SCHEMBL904515

OCc1cc(Cl)nc(Cl)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.54
ACHE P22303 1/20 0.43
S1PR2 O95136 2/20 0.39
CYP2C19 P33261 2/20 0.35
CYP2D6 P10635 1/20 0.35
FFAR1 O14842 1/20 0.34
KDM4E B2RXH2 2/20 0.33
TSHR P16473 1/20 0.33
LOX P28300 1/20 0.33
LOXL3 P58215 1/20 0.33
LOXL2 Q9Y4K0 1/20 0.33
CASP6 P55212 1/20 0.33
POLB P06746 2/20 0.32
HSP90AB1 P08238 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
HSD17B10 Q99714 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
CYP3A4 P08684 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27238074 0.85 RECQL (0.52) RECQLACHES1PR2CYP2C19CYP2D6
SCHEMBL30403081 0.85 RECQL (0.52) RECQLACHES1PR2CYP2C19CYP2D6
SCHEMBL501869 0.84 RECQL (0.45) RECQLACHECYP2C19CYP2D6KDM4E
SCHEMBL26075517 0.84 RECQL (0.45) RECQLACHECYP2C19CYP2D6POLB
SCHEMBL501235 0.84 RECQL (0.45) RECQLACHECYP2C19KDM4EPOLB
SCHEMBL190086 0.82 RECQL (0.41) RECQLS1PR2CYP2C19FFAR1KDM4E
SCHEMBL16346209 0.80 RECQL (0.47) RECQLACHECYP2C19KDM4ELOX
Hydrochloric Acid SCHEMBL6869464 0.80 RECQL (0.39) RECQLS1PR2CYP2C19FFAR1KDM4E
SCHEMBL31047280 0.79 RECQL (0.40) RECQLS1PR2CYP2C19CYP2D6FFAR1
SCHEMBL6987053 0.79 RECQL (0.40) RECQLS1PR2CYP2C19CYP2D6FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 235 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1016661-B1 2,6-DICHLORO-4-PYRIDINEMETHANOL DERIVATIVES AS AGRICULTURAL CHEMICALS DAINIPPON INK & CHEMICALS (JP) 2005-08-03 EP claimed
US-6620823-B2 Antiinflammatory agents; rheumatic disorders BRISTOL-MYERS SQUIBB PHARME COMPANY 2003-09-16 US claimed
US-6281231-B1 2,6-dichloro-4-pyridinemethanol derivatives and agricultural chemicals DAINIPPON INK AND CHEMICAL, INC. (JP) 2001-08-28 US claimed
EP-1016661-A1 2,6-DICHLORO-4-PYRIDINEMETHANOL DERIVATIVES AND AGRICULTURAL CHEMICALS DAINIPPON INK AND CHEMICALS, INC. (JP) 2000-07-05 EP claimed
JP-11171864-A None JP disclosed
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF PEPTIDREAM INC (JP) 2026-01-15 US disclosed
EP-4655296-A1 CBL-B INHIBITORS Aurigene Oncology Limited (IN) 2025-12-03 EP disclosed
US-20250282768-A1 PYRROLIDINONE DERIVATIVES AS INHIBITORS OF NF KAPPA B INDUCING KINASE JANSSEN PHARMACEUTICA NV (BE) 2025-09-11 US disclosed
US-20250277066-A1 Substituted Pyridine-2,6-Bis(Phenylenephenolate) Complexes with Enhanced Solubility that are Useful as Catalyst Components for Olefin Polymerization EXXONMOBIL CHEMICAL PATENTS INC (US) 2025-09-04 US disclosed
US-20250263399-A1 CBL-B MODULATORS AND USES THEREOF SCHRÖDINGER, INC. 2025-08-21 US disclosed
US-12325697-B2 CBL-B modulators and uses thereof NIMBUS CLIO, INC. (US) 2025-06-10 US disclosed
EP-4534524-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF PeptiDream Inc. (JP) 2025-04-09 EP disclosed
EP-0509769-B1 Heterocyclic amides having HLE inhibiting activity ZENECA LTD (GB) 1996-09-11 EP disclosed
US-5521179-A Heterocyclic amides ZENECA LIMITED (GB) 1996-05-28 US disclosed
EP-0369762-B1 Pesticides ROUSSEL UCLAF (FR) 1993-12-29 EP disclosed
US-5202356-A Insecticides, miticides THE WELLCOME FOUNDATION LIMITED (GB) 1993-04-13 US disclosed
EP-0244728-B1 USE OF HETEROARYLETHYL AMINES TO STIMULATE ANIMAL GROWTH, HETEROARYLETHYL AMINES AND PROCESS FOR THEIR PREPARATION BAYER AG (DE) 1992-11-11 EP disclosed
EP-0509769-A2 Heterocyclic amides having HLE inhibiting activity ZENECA LIMITED (GB) 1992-10-21 EP disclosed
EP-0369762-A1 Pesticides ROUSSEL-UCLAF (FR) 1990-05-23 EP disclosed
EP-0244728-A2 Use of heteroarylethyl amines to stimulate animal growth, heteroarylethyl amines and process for their preparation BAYER AG (DE) 1987-11-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250282768-A1 PYRROLIDINONE DERIVATIVES AS INHIBITORS OF NF KAPPA B INDUCING KINASE NFKBIA, IKBKG, IKBKB RECQL 2599/4885ACHE 4689/4885S1PR2 2223/4885
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF NSUN3, BCAT1, SLC43A1 RECQL 2737/4885ACHE 4849/4885S1PR2 4330/4885
US-20250263399-A1 CBL-B MODULATORS AND USES THEREOF CBLB, CBL, CBLC RECQL 2302/4885ACHE 4726/4885S1PR2 2324/4885
US-12325697-B2 CBL-B modulators and uses thereof CBLB, CBL, CBLC RECQL 2302/4885ACHE 4726/4885S1PR2 2324/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.