Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | LOX | P28300 | 1/20 | 0.31 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.31 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL904515 | 0.79 | RECQL (0.54) | RECQLS1PR2CYP2D6CYP2C19FFAR1 | |
| SCHEMBL31047279 | 0.75 | S1PR2 (0.32) | RECQLS1PR2LOXLOXL3LOXL2 | |
| SCHEMBL6987053 | 0.75 | RECQL (0.40) | RECQLS1PR2CYP2D6CYP2C19FFAR1 | |
| SCHEMBL190086 | 0.73 | RECQL (0.41) | RECQLS1PR2CYP2C19FFAR1LOX | |
| Hydrochloric Acid SCHEMBL6869464 | 0.70 | RECQL (0.39) | RECQLS1PR2CYP2C19FFAR1LOX | |
| SCHEMBL31047315 | 0.70 | — | — | |
| SCHEMBL30908293 | 0.69 | NOS1 (0.36) | RECQLCYP2C19 | |
| SCHEMBL2056128 | 0.69 | SMN1; SMN2 (0.42) | RECQLS1PR2CYP2C19LOXLOXL3 | |
| SCHEMBL855313 | 0.69 | LOXL2 (0.54) | RECQLS1PR2LOXLOXL3LOXL2 | |
| SCHEMBL5898392 | 0.69 | S1PR2 (0.39) | RECQLS1PR2CYP2C19FFAR1LOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024193689-A1 | PYRIDINOPYRROLE DERIVATIVE AND USE THEREOF IN DRUGS | 广东东阳光药业股份有限公司 | 2024-09-26 | — | — | WO | disclosed |
| CN-118684665-A | Pyridopyrrole derivatives and their use in medicine | 广东东阳光药业股份有限公司 | 2024-09-24 | — | — | CN | disclosed |