Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9045834 | 1.00 | THRB (0.34) | THRB | |
| SCHEMBL11259010 | 0.79 | DNM1 (0.45) | THRB | |
| SCHEMBL9422915 | 0.76 | THRB (0.39) | THRB | |
| SCHEMBL9422995 | 0.75 | TSHR (0.42) | THRB | |
| SCHEMBL8800116 | 0.74 | ALDH1A1 (0.53) | — | |
| SCHEMBL8798078 | 0.74 | ALDH1A1 (0.53) | — | |
| SCHEMBL4915033 | 0.72 | ALDH1A1 (0.35) | — | |
| SCHEMBL8812442 | 0.72 | DGKA (0.38) | — | |
| SCHEMBL8813681 | 0.72 | DGKA (0.38) | — | |
| SCHEMBL3179171 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536936-B1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | SANKYO CO (JP) | 1996-08-14 | — | — | EP | claimed |
| EP-0536936-B1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | SANKYO CO (JP) | 1996-08-14 | — | — | EP | disclosed |