Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.45 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | LIPE | Q05469 | 2/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3100106 | 0.90 | LIPE (0.46) | L3MBTL1HTTHAO1P2RX3MEN1 | |
| SCHEMBL27691056 | 0.87 | L3MBTL1 (0.43) | L3MBTL1HTTHAO1P2RX3MEN1 | |
| SCHEMBL14349927 | 0.85 | P2RX3 (0.48) | L3MBTL1HTTHAO1P2RX3KDM4E | |
| SCHEMBL8026494 | 0.85 | L3MBTL1 (0.44) | L3MBTL1HTTHAO1P2RX3MEN1 | |
| SCHEMBL9045204 | 0.85 | MAOB (0.53) | L3MBTL1HTTHAO1P2RX3MEN1 | |
| SCHEMBL8019976 | 0.85 | P2RX3 (0.48) | L3MBTL1HTTHAO1P2RX3EGLN1 | |
| SCHEMBL510446 | 0.84 | LTA4H (0.45) | HTTHAO1ALDH1A1LTA4H | |
| SCHEMBL25015682 | 0.82 | ALDH1A1 (0.49) | L3MBTL1HTTHAO1P2RX3EGLN1 | |
| SCHEMBL15685061 | 0.82 | MAOB (0.55) | L3MBTL1HTTHAO1P2RX3MEN1 | |
| SCHEMBL1437122 | 0.81 | LIPE (0.50) | KMT2AEGLN1DAGLAKDM4ELIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3760617-B1 | SUBSTITUTED PYRIMIDINE COMPOUND AND USES THEREOF | SHENYANG SINOCHEM AGROCHEMICALS R & D CO LTD (CN) | 2023-03-22 | — | — | EP | disclosed |
| EP-2913325-B1 | SUBSTITUTED PYRIMIDINE COMPOUND AND USES THEREOF | SHENYANG SINOCHEM AGROCHEMICALS R & D CO LTD (CN) | 2021-04-21 | — | — | EP | disclosed |
| EP-2913325-B1 | SUBSTITUTED PYRIMIDINE COMPOUND AND USES THEREOF | SHENYANG SINOCHEM AGROCHEMICALS R & D CO LTD (CN) | 2021-04-21 | — | — | EP | disclosed |
| EP-3760617-A1 | SUBSTITUTED PYRIMIDINE COMPOUND AND USES THEREOF | Shenyang Sinochem Agrochemicals R&D Co., Ltd. (CN) | 2021-01-06 | — | — | EP | disclosed |
| EP-3760617-A1 | SUBSTITUTED PYRIMIDINE COMPOUND AND USES THEREOF | Shenyang Sinochem Agrochemicals R&D Co., Ltd. (CN) | 2021-01-06 | — | — | EP | disclosed |
| US-9770026-B2 | Substituted pyrimidine compound and uses thereof | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2017-09-26 | — | — | US | disclosed |
| US-9770026-B2 | Substituted pyrimidine compound and uses thereof | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2017-09-26 | — | — | US | disclosed |
| US-9770026-B2 | Substituted pyrimidine compound and uses thereof | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2017-09-26 | — | — | US | disclosed |
| CN-104206384-B | Aminated compounds is as the application of pesticide | SHENYANG SINOCHEM PESTICIDE CHEMICAL RESEARCH AND DEVELOPMENT CO., LTD. (CN) | 2016-05-18 | — | — | CN | disclosed |
| CN-103772356-B | Replace fragrant oxy picolinate compounds and uses thereof | SHENYANG SINOCHEM PESTICIDE CHEMICAL RESEARCH AND DEVELOPMENT CO., LTD. (CN) | 2016-03-23 | — | — | CN | disclosed |
| US-20150257385-A1 | Substituted Pyrimidine Compound and Uses Thereof | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2015-09-17 | — | — | US | disclosed |
| US-20150257385-A1 | Substituted Pyrimidine Compound and Uses Thereof | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2015-09-17 | — | — | US | disclosed |
| EP-2913325-A1 | SUBSTITUTED PYRIMIDINE COMPOUND AND USES THEREOF | Sinochem Corporation (CN) | 2015-09-02 | — | — | EP | disclosed |
| EP-2913325-A1 | SUBSTITUTED PYRIMIDINE COMPOUND AND USES THEREOF | Sinochem Corporation (CN) | 2015-09-02 | — | — | EP | disclosed |
| CN-104206384-A | Use of amine compound as pesticide | SINOCHEM CORP | 2014-12-17 | — | — | CN | disclosed |
| CN-103772356-A | Substituted aryloxy pyridine compound and use thereof | SINOCHEM CORP | 2014-05-07 | — | — | CN | disclosed |
| WO-2014063642-A1 | SUBSTITUTED PYRIMIDINE COMPOUND AND USES THEREOF | 中国中化股份有限公司 (CN) | 2014-05-01 | — | — | WO | disclosed |
| EP-0199281-B1 | PYRIDAZINONE DERIVATIVES, PREPARATION THEREOF, AND INSECTICIDAL, ACARICIDAL, NEMATICIDAL, FUNGICIDAL COMPOSITIONS | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1991-07-10 | — | — | EP | disclosed |
| US-4837217-A | Pyridazinone derivatives, preparation thereof, and insecticidal, acaricidal, nematicidal, fungicidal compositions | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1989-06-06 | — | — | US | disclosed |
| EP-0199281-A2 | Pyridazinone derivatives, preparation thereof, and insecticidal, acaricidal, nematicidal, fungicidal compositions | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1986-10-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150257385-A1 | Substituted Pyrimidine Compound and Uses Thereof | TYR, GART, LRRK2 | L3MBTL1 1300/4885HTT 3037/4885HAO1 2337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.