Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9049481 | 0.87 | LMNA (0.55) | KMT2AKDM4ELMNAALDH1A1MAPT | |
| SCHEMBL9116444 | 0.80 | PGR (0.56) | KMT2AKDM4ELMNAALDH1A1MAPT | |
| SCHEMBL9049128 | 0.80 | SIRT2 (0.47) | KMT2AHSD17B10KDM4ELMNAMAPT | |
| SCHEMBL9047016 | 0.79 | HSD17B10 (0.56) | TP53KMT2AHSD17B10KDM4ELMNA | |
| SCHEMBL8189741 | 0.77 | MAPT (0.60) | KMT2AMEN1KDM4ELMNAALDH1A1 | |
| SCHEMBL9049287 | 0.77 | LMNA (0.53) | KMT2AKDM4ELMNAALDH1A1MAPT | |
| SCHEMBL9049557 | 0.77 | LMNA (0.55) | KMT2AKDM4ELMNAALDH1A1MAPT | |
| SCHEMBL9053693 | 0.76 | CYP11B1 (0.44) | PDE4APDE4BPDE4CPDE4DCYP11B1 | |
| SCHEMBL9054120 | 0.76 | SIRT2 (0.52) | KMT2A | |
| SCHEMBL9047335 | 0.75 | KMT2A (0.54) | KMT2AMEN1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0734378-A1 | AMINOSULPHONYL-PHENYL-1H-PYRROLE DERIVATIVES, METHOD OF THEIR PREPARATION AND THEIR USE | SMITHKLINE BEECHAM PLC (GB) | 1996-10-02 | — | — | EP | disclosed |
| WO-1995016674-A1 | AMINOSULPHONYL-PHENYL-1H-PYRROLE DERIVATIVES, METHOD OF THEIR PREPARATION AND THEIR USE | SMITHKLINE BEECHAM PLC (GB) | 1995-06-22 | — | — | WO | disclosed |