Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9116444 | 0.89 | PGR (0.56) | HPGDKDM4EKMT2ALMNAMAPT | |
| SCHEMBL9049128 | 0.89 | SIRT2 (0.47) | HSD17B10HPGDKDM4EKMT2ALMNA | |
| SCHEMBL9049481 | 0.88 | LMNA (0.55) | KDM4EKMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL9054120 | 0.84 | SIRT2 (0.52) | KMT2AMAPK1APEX1 | |
| SCHEMBL9053660 | 0.84 | ALDH1A1 (0.48) | HSD17B10HPGDKDM4EKMT2ALMNA | |
| SCHEMBL8189741 | 0.81 | MAPT (0.60) | KDM4EKMT2ALMNAMAPK1APEX1 | |
| SCHEMBL28939174 | 0.80 | PGR (0.55) | HSD17B10HPGDFFAR1CASP6KMT2A | |
| SCHEMBL9053739 | 0.80 | KMT2A (0.54) | KMT2ALMNANPSR1ALDH1A1 | |
| SCHEMBL9045528 | 0.79 | PDE4A (0.47) | HSD17B10KDM4EKMT2ALMNATP53 | |
| SCHEMBL9049287 | 0.79 | LMNA (0.53) | KDM4EKMT2ALMNATDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0734378-A1 | AMINOSULPHONYL-PHENYL-1H-PYRROLE DERIVATIVES, METHOD OF THEIR PREPARATION AND THEIR USE | SMITHKLINE BEECHAM PLC (GB) | 1996-10-02 | — | — | EP | disclosed |