Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9049128 | 0.90 | SIRT2 (0.47) | PGRMAPTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL9049481 | 0.90 | LMNA (0.55) | PGRMAPTALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL9047016 | 0.89 | HSD17B10 (0.56) | MAPTALDH1A1KMT2ALMNAKDM4E | |
| SCHEMBL28939174 | 0.86 | PGR (0.55) | PGRMAPTL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL9053739 | 0.85 | KMT2A (0.54) | PGRL3MBTL1ALDH1A1KMT2ALMNA | |
| SCHEMBL9054120 | 0.85 | SIRT2 (0.52) | KMT2A | |
| SCHEMBL8189741 | 0.82 | MAPT (0.60) | MAPTALDH1A1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL9045528 | 0.80 | PDE4A (0.47) | MAPTALDH1A1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL664705 | 0.80 | PGR (0.68) | PGRMAPTL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL9049287 | 0.80 | LMNA (0.53) | PGRMAPTALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995016674-A1 | AMINOSULPHONYL-PHENYL-1H-PYRROLE DERIVATIVES, METHOD OF THEIR PREPARATION AND THEIR USE | SMITHKLINE BEECHAM PLC (GB) | 1995-06-22 | — | — | WO | disclosed |