Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 4/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.43 |
| ▸ | DRD2 | P14416 | 4/20 | 0.41 |
| ▸ | DRD3 | P35462 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9053622 | 0.87 | DRD2 (0.50) | DRD2DRD3KMT2AKDM4ELMNA | |
| SCHEMBL9053039 | 0.83 | PGR (0.51) | CYP11B1CYP11B2DRD2DRD3KMT2A | |
| SCHEMBL9051914 | 0.82 | MAPT (0.42) | DRD2DRD3KMT2AMEN1KDM4E | |
| SCHEMBL9115693 | 0.82 | FFAR1 (0.46) | DRD2DRD3KMT2AHSD17B10HPGD | |
| SCHEMBL8544314 | 0.81 | MAPT (0.54) | DRD2DRD3KMT2AMEN1GAA | |
| SCHEMBL9053598 | 0.79 | SIRT2 (0.46) | DRD2DRD3KDM4ELMNAMAPT | |
| SCHEMBL9053185 | 0.78 | MAPT (0.50) | DRD2DRD3KMT2AKDM4ELMNA | |
| SCHEMBL9054157 | 0.78 | DRD2 (0.41) | DRD2DRD3KMT2AMEN1HPGD | |
| SCHEMBL9060714 | 0.76 | ALDH1A1 (0.39) | DRD2DRD3KMT2AMEN1HSD17B10 | |
| SCHEMBL9045528 | 0.76 | PDE4A (0.47) | CYP11B1CYP11B2PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0734378-A1 | AMINOSULPHONYL-PHENYL-1H-PYRROLE DERIVATIVES, METHOD OF THEIR PREPARATION AND THEIR USE | SMITHKLINE BEECHAM PLC (GB) | 1996-10-02 | — | — | EP | disclosed |