Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9045438 | 0.84 | BCL2L1 (0.55) | MAPTLMNAGAAALDH1A1KDM4E | |
| SCHEMBL2431312 | 0.79 | MAPT (0.52) | MAPTLMNAGAAALDH1A1KDM4E | |
| SCHEMBL8323119 | 0.72 | MCL1 (0.66) | MAPTLMNAGAAALDH1A1KDM4E | |
| SCHEMBL8020988 | 0.72 | CYP4F2 (0.54) | MAPTLMNAGAAALDH1A1KDM4E | |
| SCHEMBL9203348 | 0.70 | MCL1 (0.57) | MAPTLMNAGAAALDH1A1KDM4E | |
| SCHEMBL19283514 | 0.69 | MCL1 (0.59) | MAPTLMNAGAAALDH1A1KDM4E | |
| SCHEMBL9204281 | 0.69 | MCL1 (0.56) | MAPTLMNAGAAALDH1A1KDM4E | |
| SCHEMBL5228832 | 0.67 | BCKDK (0.61) | MAPTLMNAALDH1A1KDM4EMAPK1 | |
| SCHEMBL13520157 | 0.67 | TRPA1 (0.32) | ALDH1A1TSHR | |
| SCHEMBL11468756 | 0.66 | MCL1 (0.55) | MAPTLMNAGAAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0595150-B1 | Process for the preparation of aromatic bromomethylcompounds | HOECHST AG (DE) | 1996-07-31 | — | — | EP | disclosed |
| EP-0595150-A1 | Process for the preparation of aromatic bromomethylcompounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-05-04 | — | — | EP | disclosed |