Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TOP1 | P11387 | 4/20 | 0.37 |
| ▸ | PIM1 | P11309 | 2/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.31 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9057013 | 0.86 | HTT (0.46) | ALDH1A1HTTSTAT3POLBKDM4E | |
| SCHEMBL9044750 | 0.84 | ALDH1A1 (0.41) | ALDH1A1HTTTOP1STAT3POLB | |
| SCHEMBL9047265 | 0.83 | ALDH1A1 (0.40) | ALDH1A1HTTTOP1PIM1STAT3 | |
| SCHEMBL9047564 | 0.83 | ALDH1A1 (0.40) | ALDH1A1HTTTOP1STAT3POLB | |
| SCHEMBL9045879 | 0.83 | ALDH1A1 (0.40) | ALDH1A1HTTTOP1STAT3POLB | |
| SCHEMBL9045282 | 0.77 | LMNA (0.43) | ALDH1A1HTTTOP1POLBKDM4E | |
| SCHEMBL9046944 | 0.73 | ALDH1A1 (0.53) | ALDH1A1HTTTOP1STAT3POLB | |
| SCHEMBL9046043 | 0.71 | STAT3 (0.54) | ALDH1A1HTTTOP1STAT3POLB | |
| SCHEMBL9048751 | 0.71 | TOP1 (0.45) | ALDH1A1HTTTOP1PIM1POLB | |
| SCHEMBL9045934 | 0.70 | HTT (0.46) | ALDH1A1HTTSTAT3KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700912-A1 | QUINOLONE DERIVATIVE OR SALT THEREOF, AND ANTIBACTERIAL CONTAINING THE SAME | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1996-03-13 | — | — | EP | disclosed |