Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 1/20 | 0.71 |
| ▸ | CTNNB1 | P35222 | 5/20 | 0.69 |
| ▸ | WNT3A | P56704 | 5/20 | 0.69 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | KDM1A | O60341 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.55 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.53 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557156 | 0.90 | ADAM17 (0.68) | ADAM17CTNNB1WNT3AGPR84LMNA | |
| SCHEMBL4852469 | 0.89 | ADAM17 (0.66) | ADAM17CTNNB1WNT3AGPR84LMNA | |
| SCHEMBL3717752 | 0.88 | ADAM17 (0.68) | ADAM17CTNNB1WNT3AGPR84LMNA | |
| SCHEMBL9633079 | 0.85 | ADAM17 (0.73) | ADAM17CTNNB1WNT3AGPR84LMNA | |
| SCHEMBL7214385 | 0.83 | ADAM17 (1.00) | ADAM17CTNNB1WNT3AGPR84LMNA | |
| SCHEMBL15969761 | 0.82 | CTNNB1 (1.00) | ADAM17CTNNB1WNT3AGPR84LMNA | |
| SCHEMBL4056357 | 0.81 | ADAM17 (0.68) | ADAM17CTNNB1WNT3AGPR84LMNA | |
| SCHEMBL32685253 | 0.81 | ADAM17 (0.68) | ADAM17CTNNB1WNT3AGPR84LMNA | |
| SCHEMBL12838313 | 0.81 | ADAM17 (0.68) | ADAM17CTNNB1WNT3AGPR84LMNA | |
| SCHEMBL28751191 | 0.81 | GABRA1 (0.81) | ADAM17CTNNB1WNT3AGPR84LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9714232-B2 | Substituted piperazine compounds and methods of use thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2017-07-25 | — | — | US | disclosed |
| US-20160244429-A1 | Substituted Piperazine Compounds And Methods Of Use Thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-08-25 | — | — | US | disclosed |
| EP-0714896-A1 | INDOL DERIVATIVES USEFUL FOR THE TREATMENT OF MIGRAINE, COMPOSITION AND UTILIZATION | VITA-INVEST, S.A. (ES) | 1996-06-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160244429-A1 | Substituted Piperazine Compounds And Methods Of Use Thereof | HTR5A, HTR2A, HTR2C | ADAM17 3241/4885CTNNB1 4188/4885WNT3A 1539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.