Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | GSK3B | P49841 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | RAF1 | P04049 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1515726 | 0.84 | NPC1 (0.62) | POLBMAPTKDM4EGSK3BALDH1A1 | |
| SCHEMBL11267020 | 0.83 | NPC1 (0.57) | POLBMAPTGSK3BALDH1A1KMT2A | |
| SCHEMBL11506839 | 0.82 | LMNA (0.62) | POLBMAPTKDM4EGSK3BALDH1A1 | |
| SCHEMBL18437367 | 0.81 | ALDH1A1 (0.58) | POLBMAPTKDM4EGSK3BALDH1A1 | |
| SCHEMBL1554434 | 0.80 | TDP1 (0.55) | POLBMAPTKDM4EGSK3BALDH1A1 | |
| SCHEMBL7038772 | 0.79 | MEN1 (0.64) | POLBMAPTALDH1A1KMT2ARAB9A | |
| SCHEMBL1436692 | 0.79 | ALDH1A1 (0.51) | POLBMAPTKDM4EGSK3BALDH1A1 | |
| SCHEMBL15988711 | 0.78 | LMNA (0.70) | POLBMAPTGSK3BALDH1A1KMT2A | |
| SCHEMBL7200564 | 0.78 | RAB9A (0.67) | POLBMAPTGSK3BALDH1A1KMT2A | |
| Sulfamide SCHEMBL6420737 | 0.77 | POLB (0.53) | POLBMAPTKDM4EGSK3BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0339599-B1 | Process for producing acylaromatic compounds | SUMITOMO CHEMICAL CO (JP) | 1996-08-21 | — | — | EP | disclosed |
| EP-0339599-A2 | Process for producing acylaromatic compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-11-02 | — | — | EP | disclosed |
| US-4159338-A | ANTIARTHRITIC, ANALGESIC | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-06-26 | — | — | US | disclosed |