SCHEMBL1554434

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9048735	0.80	POLB (0.61)	GSK3BALDH1A1POLBNPC1RAB9A
	SCHEMBL11506839	0.76	LMNA (0.62)	GSK3BALDH1A1POLBNPC1RAB9A
	SCHEMBL1554856	0.75	L3MBTL1 (0.53)	GSK3BALDH1A1NPC1RAB9ASMN1; SMN2
	SCHEMBL18437367	0.74	ALDH1A1 (0.58)	GSK3BALDH1A1POLBNPC1RAB9A
	SCHEMBL1515726	0.74	NPC1 (0.62)	GSK3BALDH1A1POLBNPC1RAB9A
	SCHEMBL27589844	0.73	TDP1 (0.45)	TDP1ALDH1A1NPC1RAB9ALMNA
	SCHEMBL11267020	0.73	NPC1 (0.57)	GSK3BALDH1A1POLBNPC1RAB9A
	SCHEMBL30154481	0.72	GABRP (0.61)	ALDH1A1NPC1RAB9ALMNAKMT2A
	SCHEMBL256024	0.72	GABRP (0.61)	ALDH1A1NPC1RAB9ALMNAKMT2A
	SCHEMBL1257317	0.72	ALDH1A1 (0.47)	TDP1ALDH1A1POLBNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.