Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9048669 | 0.80 | MEN1 (0.42) | ALDH1A1HTT | |
| SCHEMBL9048458 | 0.78 | PTGIR (0.45) | ALDH1A1LTB4R2ATMCHRM2CHRM1 | |
| SCHEMBL9048927 | 0.73 | PTGIR (0.43) | ALDH1A1 | |
| SCHEMBL9427323 | 0.72 | SIGMAR1 (0.40) | ALDH1A1HTT | |
| SCHEMBL9048014 | 0.70 | PTGIR (0.43) | ALDH1A1LTB4R2HTT | |
| SCHEMBL9047848 | 0.70 | PTGIR (0.43) | ALDH1A1 | |
| SCHEMBL9427077 | 0.69 | SIGMAR1 (0.44) | ALDH1A1LTB4R2NPC1HTT | |
| SCHEMBL9049799 | 0.69 | F11 (0.42) | ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL9046465 | 0.68 | PRMT5 (0.41) | — | |
| SCHEMBL9427490 | 0.68 | MEN1 (0.39) | ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | claimed |