Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7682549 | 0.87 | GAA (0.41) | GAAMAPTLMNAHPGDSMN1; SMN2 | |
| SCHEMBL2901109 | 0.87 | GAA (0.42) | GAAMAPTLMNAHPGDSMN1; SMN2 | |
| SCHEMBL10471483 | 0.85 | LMNA (0.40) | GAAMAPTLMNAHPGDSMN1; SMN2 | |
| SCHEMBL10913907 | 0.84 | MAPT (0.38) | GAAMAPTLMNAHPGDSMN1; SMN2 | |
| SCHEMBL10913911 | 0.84 | TSHR (0.41) | GAAMAPTLMNAHPGDSMN1; SMN2 | |
| SCHEMBL9492204 | 0.82 | KEAP1 (0.38) | MAPTLMNAHPGDSMN1; SMN2POLB | |
| SCHEMBL9419230 | 0.81 | POLB (0.33) | MAPTHPGDSMN1; SMN2POLBAPEX1 | |
| SCHEMBL2903057 | 0.81 | ALDH1A1 (0.39) | MAPTHPGDPOLBKMT2AALDH1A1 | |
| SCHEMBL9770905 | 0.80 | NAAA (0.39) | GAAMAPTLMNAHPGDSMN1; SMN2 | |
| SCHEMBL8603030 | 0.78 | CUL4A (0.40) | GAAMAPTLMNAHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705267-A1 | HERBICIDAL THIADIAZABICYCLODECANES | CIBA GEIGY AG (CH) | 1996-04-10 | — | — | EP | disclosed |