Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9492204 | 0.86 | KEAP1 (0.38) | POLBAPEX1HPGDMAPTTSHR | |
| SCHEMBL9419231 | 0.81 | — | — | |
| SCHEMBL9051631 | 0.81 | GAA (0.40) | POLBAPEX1HPGDMAPTTSHR | |
| SCHEMBL10471483 | 0.77 | LMNA (0.40) | POLBAPEX1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL8816731 | 0.76 | — | — | |
| SCHEMBL11552834 | 0.76 | KDM1A (0.36) | HPGD | |
| SCHEMBL9770905 | 0.76 | NAAA (0.39) | POLBHPGDMAPTSMN1; SMN2NPC1 | |
| SCHEMBL8599218 | 0.75 | — | — | |
| SCHEMBL8601376 | 0.75 | HPGD (0.37) | HPGDTSHR | |
| SCHEMBL10913911 | 0.74 | TSHR (0.41) | HPGDMAPTTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310722-A | Synergistic composition comprising a sulfonylurea and a thiadiazolo[3,4-a]py | CIBA-GEIGY CORPORATION (US) | 1994-05-10 | — | — | US | disclosed |
| US-5229514-A | Thiourea compounds containing pyridazine ring | CIBA-GEIGY CORPORATION (US) | 1993-07-20 | — | — | US | disclosed |
| US-5135562-A | 8-thia-1,6-diazabicyclo[4.3.0]nonane herbicides | CIBA-GEIGY CORPORATION (US) | 1992-08-04 | — | — | US | disclosed |