Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27892746 | 0.87 | ALDH1A1 (0.60) | ALDH1A1MAPTHTTSMN1; SMN2POLB | |
| SCHEMBL20106885 | 0.82 | ALDH1A1 (0.60) | ALDH1A1MAPTHTTSMN1; SMN2POLB | |
| SCHEMBL5396452 | 0.79 | LMNA (0.63) | ALDH1A1MAPTLMNAATMHTR1A | |
| SCHEMBL9052600 | 0.77 | HTT (0.71) | ALDH1A1MAPTHTTSMN1; SMN2POLB | |
| SCHEMBL28667202 | 0.77 | GPR119 (0.49) | ALDH1A1MAPTSMN1; SMN2LMNAMEN1 | |
| SCHEMBL28670604 | 0.76 | ALDH1A1 (0.45) | ALDH1A1MAPTHTTSMN1; SMN2POLB | |
| SCHEMBL20180504 | 0.74 | NPSR1 (0.53) | ALDH1A1MAPTHTTSMN1; SMN2POLB | |
| SCHEMBL630705 | 0.74 | KMT2A (0.70) | ALDH1A1MAPTHTTSMN1; SMN2POLB | |
| SCHEMBL283988 | 0.73 | ALDH1A1 (0.52) | ALDH1A1MAPTHTTSMN1; SMN2POLB | |
| SCHEMBL15316122 | 0.73 | ALDH1A1 (0.61) | ALDH1A1MAPTHTTSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996041802-A1 | NOVEL HETEROAROMATIC PIPERAZINES FOR USE AS DRUGS | PIERRE FABRE MEDICAMENT (FR) | 1996-12-27 | — | — | WO | claimed |
| WO-1996041802-A1 | NOVEL HETEROAROMATIC PIPERAZINES FOR USE AS DRUGS | PIERRE FABRE MEDICAMENT (FR) | 1996-12-27 | — | — | WO | disclosed |