Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Benzene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.75 |
| ▸ | TP53 | P04637 | 1/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL17667988 | 1.00 | TSHR (0.75) | TSHRTP53ALDH1A1NAPRTTDP1 | |
| Benzene SCHEMBL9691214 | 1.00 | TSHR (0.75) | TSHRTP53ALDH1A1NAPRTTDP1 | |
| Benzene SCHEMBL11806105 | 1.00 | TSHR (0.75) | TSHRTP53ALDH1A1NAPRTTDP1 | |
| Benzene SCHEMBL525713 | 1.00 | — | — | |
| Benzene SCHEMBL9239251 | 1.00 | — | — | |
| Benzene SCHEMBL10829587 | 1.00 | TSHR (0.75) | TSHRTP53ALDH1A1NAPRTTDP1 | |
| Benzene SCHEMBL27448013 | 1.00 | TSHR (0.75) | TSHRTP53ALDH1A1NAPRTTDP1 | |
| Benzene SCHEMBL11577988 | 1.00 | TSHR (0.75) | TSHRTP53ALDH1A1NAPRTTDP1 | |
| Benzene SCHEMBL28756748 | 0.89 | TP53 (0.60) | TSHRTP53 | |
| Benzene SCHEMBL28600795 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 731 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122060164-A | Perfluoro-cyclobutyl polyether sulfone polymer and preparation method thereof | 江苏三吉利化工股份有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122060163-A | Novel fluorine-containing polyether sulfone ketone polymer and preparation method thereof | 江苏三吉利化工股份有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122037196-A | Perfluoro-cyclobutyl polyethersulfone ketone polymer and preparation method thereof | 江苏三吉利化工股份有限公司 | 2026-05-15 | — | — | CN | claimed |
| WO-2024119493-A1 | PREPARATION METHOD FOR IMMUNOMAGNETIC BEAD TEST STRIP FOR RAPIDLY DETECTING TRACE PROTEIN IN CULTURAL RELICS, AND APPLICATION THEREOF | 中国丝绸博物馆 | 2024-06-13 | — | — | WO | claimed |
| CN-118126322-A | High-energy-storage polyetherimide dielectric material, preparation method and application thereof | 陕西科技大学 | 2024-06-04 | — | — | CN | claimed |
| CN-117964555-A | Bisamide derivative containing phenyl ether bond, and preparation method and application thereof | 南开大学 | 2024-05-03 | — | — | CN | claimed |
| WO-2023168684-A1 | METHOD FOR PREPARING QUANTUM DOT, AND QUANTUM DOT AND DISPLAY DEVICE | 京东方科技集团股份有限公司 | 2023-09-14 | — | — | WO | claimed |
| CN-116356578-A | Building membrane material and preparation method thereof | 四川川交路桥有限责任公司 | 2023-06-30 | — | — | CN | claimed |
| CN-113582830-A | Method for efficiently stripping impurities and purifying acrylic acid | 山东蓝湾新材料有限公司 | 2021-11-02 | — | — | CN | claimed |
| CN-104803896-B | Contain two（Benzene sulfuryl）Conjugated compound of benzene structure and its preparation method and application | 深圳市华星光电技术有限公司 | 2017-07-28 | — | — | CN | claimed |
| CN-101343216-A | Method for preparing insecticide ethofenprox | BEIJING CHARNA CHEMICALS LTD (CN) | 2009-01-14 | — | — | CN | claimed |
| CN-1813953-A | Chinese medicine formulation for promoting blood circulation to arrest pain, and its preparing method and quality control method | WANG HENGXIN (CN) | 2006-08-09 | — | — | CN | claimed |
| US-6231844-B1 | FOAMING HAIR MOUSSE COMPRISING AT LEAST A POLYOXYETHYLENE AND/OR POLYOXYPROPYLENE TYPE OF NONIONIC SURFACTANT WHICH HAS A TOTAL HYDROPHILC-LIPOPHILIC BALANCE BY GRIFFIN METHOD OF ATLEAST 12, PROVIDES STABLE FOAMING AND SMOOTH, MILD TOUCH | THE PROCTER & GAMBLE COMPANY | 2001-05-15 | — | — | US | claimed |
| CN-1196045-A | Process for nitrating diphenyl ether compounds | ZENECA LTD (GB) | 1998-10-14 | — | — | CN | claimed |
| EP-0440444-B1 | Photosensitive resin composition | NIPPON PAINT CO LTD (JP) | 1996-12-27 | — | — | EP | claimed |
| CN-1133859-A | Stabilizer combination | CIBA GEIGY AG (CH) | 1996-10-23 | — | — | CN | claimed |
| US-5204221-A | Crosslinked vinyl polymer and unsaturated monomer; for flexographic printing, printed circuits; storage stability and water developability | NIPPON PAINT CO., LTD. (JP) | 1993-04-20 | — | — | US | claimed |
| EP-0440444-A2 | Photosensitive resin composition | NIPPON PAINT CO., LTD. (JP) | 1991-08-07 | — | — | EP | claimed |
| EP-0185578-B1 | PROCESS FOR THE PREPARATION OF ACTIVE CARBOXYLIC-ACID ESTERS, ALPHA-HALOGENATED CARBONATES USEFUL FOR THIS PREPARATION AND THEIR PREPARATION | SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) | 1990-10-03 | — | — | EP | claimed |
| EP-0185578-A1 | Process for the preparation of active carboxylic-acid esters, alpha-halogenated carbonates useful for this preparation and their preparation | SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) | 1986-06-25 | — | — | EP | claimed |