Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | COMT | P21964 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9051768 | 0.79 | SCD (0.50) | ALDH1A1LMNASMN1; SMN2HTTMEN1 | |
| SCHEMBL29103216 | 0.76 | ALDH1A1 (0.56) | ALDH1A1LMNASMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL9051881 | 0.71 | LMNA (0.46) | ALDH1A1LMNASMN1; SMN2HTTMEN1 | |
| SCHEMBL24828541 | 0.68 | L3MBTL1 (0.59) | ALDH1A1LMNASMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL25378342 | 0.68 | ALDH1A1 (0.48) | ALDH1A1LMNASMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL9950869 | 0.67 | — | — | |
| SCHEMBL9050273 | 0.67 | P2RX7 (0.45) | ALDH1A1SMN1; SMN2HTTL3MBTL1MEN1 | |
| SCHEMBL116289 | 0.66 | — | — | |
| SCHEMBL18380176 | 0.66 | SMN1; SMN2 (0.42) | ALDH1A1LMNASMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL9052432 | 0.65 | GBA1 (0.42) | ALDH1A1HTTGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996034591-A1 | DIAMINOPYRAZOLE-CONTAINING COMPOSITIONS FOR COLOURING KERATIN FIBRES, COLOURING PROCESS, NOVEL DIAMINOPYRAZOLES AND METHOD FOR THEIR PREPARATION | L'OREAL (FR) | 1996-11-07 | — | — | WO | claimed |