Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MLNR | O43193 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9053431 | 0.89 | LMNA (0.38) | LMNAMLNRCYP2D6KDM4EHPGD | |
| SCHEMBL9053434 | 0.86 | EIF4E (0.39) | LMNAKDM4EHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL9058459 | 0.75 | DVL1 (0.39) | KDM4EHPGDALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL9056734 | 0.71 | RXRA (0.44) | LMNAFFAR4RXRARXRBRXRG | |
| Hydrochloric Acid SCHEMBL20509927 | 0.69 | RXRA (0.50) | MLNRCYP2D6RXRARXRBRXRG | |
| Succinic Acid SCHEMBL174914 | 0.63 | HTR2C (0.45) | MLNRCYP2D6ALDH1A1RXRARXRB | |
| SCHEMBL20510025 | 0.63 | PLAU (0.53) | RXRARXRBRXRG | |
| SCHEMBL9408051 | 0.63 | LMNA (0.55) | LMNAKDM4EHPGDALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9057948 | 0.62 | DVL1 (0.56) | LMNAKDM4EHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL9555570 | 0.62 | LMNA (1.00) | LMNAKDM4EHPGDALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996004271-A1 | CONDENSED AZEPINE DERIVATIVES, DRUGS CONTAINING THESE COMPOUNDS AND METHODS FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1996-02-15 | — | — | WO | disclosed |