Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SHMT1 | P34896 | 2/20 | 0.33 |
| ▸ | SHMT2 | P34897 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | DVL1 | O14640 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | MLNR | O43193 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9053277 | 0.89 | LMNA (0.43) | LMNAKDM4EHPGDALDH1A1GAA | |
| SCHEMBL9058459 | 0.86 | DVL1 (0.39) | KDM4EHPGDALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9053434 | 0.75 | EIF4E (0.39) | LMNAKDM4EHPGDALDH1A1MAPT | |
| SCHEMBL9056734 | 0.71 | RXRA (0.44) | LMNAFFAR4 | |
| Hydrochloric Acid SCHEMBL20509927 | 0.69 | RXRA (0.50) | MLNRCYP2D6 | |
| Succinic Acid SCHEMBL174914 | 0.63 | HTR2C (0.45) | ALDH1A1MLNRCYP2D6 | |
| SCHEMBL9408051 | 0.63 | LMNA (0.55) | LMNAKDM4EHPGDALDH1A1GAA | |
| SCHEMBL20510025 | 0.63 | PLAU (0.53) | — | |
| Hydrochloric Acid SCHEMBL9057948 | 0.62 | DVL1 (0.56) | LMNAKDM4EHPGDALDH1A1MAPT | |
| SCHEMBL9555508 | 0.62 | LMNA (0.73) | LMNAKDM4EHPGDALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996004271-A1 | CONDENSED AZEPINE DERIVATIVES, DRUGS CONTAINING THESE COMPOUNDS AND METHODS FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1996-02-15 | — | — | WO | disclosed |