Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DVL1 | O14640 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | EIF4E | P06730 | 13/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | CDC25A | P30304 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | CDC25C | P30307 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9053434 | 0.89 | EIF4E (0.39) | DVL1ALDH1A1MEN1NPC1RAB9A | |
| SCHEMBL9053431 | 0.86 | LMNA (0.38) | DVL1ALDH1A1TP53MAPTHPGD | |
| SCHEMBL9053277 | 0.75 | LMNA (0.43) | ALDH1A1TP53HPGDSMN1; SMN2KDM4E | |
| SCHEMBL9055466 | 0.75 | ALDH1A1 (0.46) | DVL1ALDH1A1MEN1RAB9AKMT2A | |
| Hydrochloric Acid SCHEMBL9057948 | 0.72 | DVL1 (0.56) | DVL1ALDH1A1MEN1NPC1RAB9A | |
| SCHEMBL9056734 | 0.71 | RXRA (0.44) | — | |
| SCHEMBL9056444 | 0.70 | HPGDS (0.41) | DVL1ALDH1A1MEN1NPC1RAB9A | |
| SCHEMBL9056435 | 0.70 | HPGDS (0.41) | DVL1ALDH1A1MEN1NPC1RAB9A | |
| SCHEMBL9056558 | 0.64 | RXRA (0.42) | DVL1 | |
| Hydrochloric Acid SCHEMBL20509927 | 0.64 | RXRA (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996004271-A1 | CONDENSED AZEPINE DERIVATIVES, DRUGS CONTAINING THESE COMPOUNDS AND METHODS FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1996-02-15 | — | — | WO | disclosed |