Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.51 |
| ▸ | DRD3 | P35462 | 3/20 | 0.51 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9053380 | 0.92 | CYP2D6 (0.43) | HTR1AHTR1DHTR1BTP53MAPT | |
| SCHEMBL6305703 | 0.84 | CHRM1 (0.53) | DRD2DRD3HTR1AHTR1DHTR1B | |
| SCHEMBL6308342 | 0.76 | CHRM1 (0.62) | TP53MAPT | |
| SCHEMBL6308077 | 0.75 | HTR1A (0.53) | DRD2DRD3HTR1AHTR1DHTR1B | |
| SCHEMBL6308232 | 0.72 | RAB9A (0.55) | HTR1AHTR1DHTR1BTP53MAPT | |
| SCHEMBL9055201 | 0.70 | HTR1A (0.52) | HTR1AHTR1DHTR1BMAPTKDM4E | |
| SCHEMBL9052843 | 0.70 | HTR1A (0.49) | DRD2HTR1AHTR1DHTR1BTP53 | |
| SCHEMBL8077724 | 0.70 | L3MBTL1 (0.39) | HTR1AHTR1DHTR1BMAPTKDM4E | |
| SCHEMBL8467046 | 0.69 | KCNH2 (0.74) | DRD2HTR1AKCNH2 | |
| SCHEMBL30764776 | 0.69 | KCNH2 (0.74) | DRD2HTR1AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0689536-A1 | NAPHTHALENE DERIVATIVES | PFIZER INC. (US) | 1996-01-03 | — | — | EP | disclosed |