Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 8/20 | 0.60 |
| ▸ | CTSK | P43235 | 8/20 | 0.60 |
| ▸ | CTSL | P07711 | 7/20 | 0.60 |
| ▸ | CTSB | P07858 | 4/20 | 0.53 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.50 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.49 |
| ▸ | REN | P00797 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
| ▸ | MMP7 | P09237 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | HPN | P05981 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31086879 | 0.83 | CTSL (0.62) | CTSSCTSKCTSLCTSBLARS1 | |
| SCHEMBL9055261 | 0.81 | CTSS (0.59) | CTSSCTSKCTSLCTSBADAMTS4 | |
| SCHEMBL9053962 | 0.81 | CTSK (0.58) | CTSSCTSKCTSLCTSBADAMTS4 | |
| SCHEMBL15251807 | 0.80 | MMP2 (0.70) | CTSSCTSKCTSLADAMTS4LARS1 | |
| SCHEMBL6561338 | 0.80 | MMP2 (0.70) | CTSSCTSKCTSLADAMTS4LARS1 | |
| SCHEMBL5191083 | 0.80 | MMP2 (0.70) | CTSSCTSKCTSLADAMTS4LARS1 | |
| SCHEMBL16388801 | 0.78 | CTSL (0.57) | CTSSCTSKCTSLCTSBADAMTS4 | |
| SCHEMBL7400910 | 0.77 | CTSS (0.69) | CTSSCTSKCTSLCTSBREN | |
| SCHEMBL8406545 | 0.77 | CTSL (0.56) | CTSSCTSKCTSLCTSBADAMTS4 | |
| SCHEMBL31086764 | 0.76 | MMP2 (0.71) | CTSSCTSKCTSLADAMTS4MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623627-B1 | Sulfonamide derivatives | MITSUBISHI CHEM CORP (JP) | 1996-11-13 | — | — | EP | disclosed |
| US-5506243-A | CYSTEINE PROTEASE INHIBITOR | MITSUBISHI KASEI CORPORATION (JP) | 1996-04-09 | — | — | US | disclosed |
| EP-0623627-A1 | Sulfonamide derivatives | Mitsubishi Chemical Corporation (JP) | 1994-11-09 | — | — | EP | disclosed |