SCHEMBL905504

SCHEMBL905504

C=COC(=O)C(C=C)N1CCCC1=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA3 P07451 1/20 0.40
CA4 P22748 1/20 0.40
CA6 P23280 1/20 0.40
CA5A P35218 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40
CA13 Q8N1Q1 1/20 0.40
CA14 Q9ULX7 1/20 0.40
CA5B Q9Y2D0 1/20 0.40
ALDH1A1 P00352 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
MAPT P10636 1/20 0.31
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29130540 0.94 LMNA (0.35) LMNACA12CA1CA2CA3
SCHEMBL8393138 0.84 LMNA (0.41) LMNACA12CA1CA2CA3
SCHEMBL9842718 0.82 LMNA (0.48) LMNACA12CA1CA2CA3
SCHEMBL5768011 0.80 LMNA (0.44) LMNACA12CA1CA2CA3
SCHEMBL4607223 0.76 LMNA (0.41) LMNACA12CA1CA2CA3
SCHEMBL28790145 0.73 SLC6A2 (0.33) LMNAALDH1A1MEN1KMT2A
SCHEMBL8443526 0.73 LMNA (0.48) LMNACA12CA1CA2CA3
SCHEMBL169032 0.71 LMNA (0.43) LMNACA12CA1CA2CA3
SCHEMBL22228539 0.70 LMNA (0.42) LMNACA12CA1CA2CA3
SCHEMBL28225063 0.70 LMNA (0.33) LMNACA12CA1CA2CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10947483-B2 Encapsulates PROCTER & GAMBLE INTERNATIONAL OPERATIONS SA (CH) 2021-03-16 US claimed
US-10604728-B2 Encapsulates PROCTER & GAMBLE INTERNATIONAL OPERATIONS SA (CH) 2020-03-31 US claimed
US-20200071639-A1 Encapsulates PROCTER & GAMBLE INT OPERATIONS SA (CH) 2020-03-05 US claimed
CN-108165030-A A kind of aqueous polymer pitch colloid and preparation method thereof 江苏荣成路桥材料有限公司 2018-06-15 CN claimed
US-20170130172-A1 ENCAPSULATES PROCTER & GAMBLE (US) 2017-05-11 US claimed
US-9475974-B2 Controlling the stability of water in water emulsions SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2016-10-25 US claimed
CN-103052386-B Compositions containing tetracyclic compound CHUGAI PHARMACEUTICAL CO.,LTD. (JP) 2016-03-02 CN claimed
WO-2014189980-A1 ENCAPSULATES PGIOSA (CH) 2014-11-27 WO claimed
EP-2806018-A1 ENCAPSULATES The Procter & Gamble Company (US) 2014-11-26 EP claimed
US-20140342972-A1 ENCAPSULATES THE PROCTER & GAMBLE COMPANY (US) 2014-11-20 US claimed
US-20100255102-A1 STERILIZATION OF DISPERSIONS OF NANOPARTICULATE ACTIVE AGENTS WITH GAMMA RADIATION ELAN PHARMA INTERNATIONAL LIMITED 2010-10-07 US claimed
US-7507400-B2 Water soluble depilatory having extended shelf life SPINA THOMAS N 2009-03-24 US claimed
WO-2006076097-A2 STABLE NON-CRYSTALLINE FORMULATION COMPRISING LOSARTAN NEKTAR THERAPEUTICS (US) 2006-07-20 WO claimed
US-20060160871-A1 Stable non-crystalline formulation comprising losartan NEKTAR THERAPEUTICS (US) 2006-07-20 US claimed
US-20050129964-A1 Outer surface thereof being coated such that it reflects sunlight in near-infrared region, and inner surface thereof having low thermal emissivity; corrosion resistance CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2005-06-16 US claimed
EP-1137722-B1 COATING WITH SPECTRAL SELECTIVITY HUGO GERD (DE) 2004-08-04 EP claimed
US-20030004522-A1 Water soluble depilatory having extended shelf life SPINA THOMAS N (US) 2003-01-02 US claimed
US-20020188051-A1 Coating with spectral selectivity CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2002-12-12 US claimed
EP-0487350-B1 Coated receiver sheets XEROX CORP (US) 1996-03-13 EP claimed
EP-0064388-B1 RETARD ORAL PHARMACEUTICAL COMPOSITIONS CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) 1985-11-06 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200071639-A1 Encapsulates LIPA, TTPA, CHMP4B LMNA 1015/4885CA12 1532/4885CA1 3244/4885
US-10947483-B2 Encapsulates LIPA, TTPA, CHMP4B LMNA 1015/4885CA12 1532/4885CA1 3244/4885
US-20060160871-A1 Stable non-crystalline formulation comprising losartan REN, AGTR1, AGTR2 LMNA 373/4885CA12 2813/4885CA1 2355/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.