Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6700097 | 0.92 | MMP2 (0.32) | MMP2NPC1RAB9A | |
| SCHEMBL3379728 | 0.83 | USP1 (0.41) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL6699829 | 0.78 | NPC1 (0.40) | NPC1RAB9AHPGDALDH1A1GAA | |
| SCHEMBL19472340 | 0.72 | IKBKB (0.35) | MMP2NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL30320817 | 0.72 | CES2 (0.47) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL9461852 | 0.68 | CES2 (0.47) | NPC1RAB9ASMN1; SMN2HPGDGAA | |
| SCHEMBL2876279 | 0.66 | — | — | |
| SCHEMBL6695032 | 0.64 | RAB9A (0.35) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL10448205 | 0.64 | NPC1 (0.45) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL12731994 | 0.64 | MAPT (0.51) | MMP2NPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8027132-A | — | — | None | — | — | JP | disclosed |
| JP-H0827132-A | PRODUCTION OF 5-OXAZOLONES | SHIRATORI SEIYAKU KK | 1996-01-30 | — | — | JP | disclosed |