Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.65 |
| ▸ | DRD2 | P14416 | 5/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.61 |
| ▸ | DRD3 | P35462 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9055949 | 0.89 | HTR1A (0.65) | HTR1ADRD2ADRA1ADRD3LMNA | |
| SCHEMBL74384 | 0.83 | ADRA1A (0.85) | HTR1ADRD2ADRA1ADRD3 | |
| SCHEMBL5945818 | 0.79 | HTR1A (1.00) | HTR1ADRD2ADRA1ADRD3LMNA | |
| SCHEMBL25607591 | 0.78 | LMNA (0.63) | HTR1ADRD2ADRA1ALMNAALDH1A1 | |
| SCHEMBL8001303 | 0.77 | ADRA1A (0.69) | HTR1ADRD2ADRA1ADRD3DRD4 | |
| SCHEMBL12040648 | 0.77 | ALDH1A1 (0.57) | HTR1ADRD2ADRA1ALMNAALDH1A1 | |
| SCHEMBL6936848 | 0.77 | HTR1A (0.67) | HTR1ADRD2ADRA1ADRD3LMNA | |
| SCHEMBL8017069 | 0.77 | DRD2 (0.94) | HTR1ADRD2ADRA1ADRD3HTR2A | |
| Dinitrophenylene SCHEMBL28029519 | 0.77 | LTA4H (0.47) | HTR1ALMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6934206 | 0.77 | HTR1A (0.67) | HTR1ADRD2ADRA1ADRD3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996001656-A1 | 5-HT1A LIGANDS | JOHN WYETH & BROTHER LIMITED (GB) | 1996-01-25 | — | — | WO | disclosed |