Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TNF | P01375 | 1/20 | 0.45 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.45 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | FPR2 | P25090 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9057217 | 1.00 | FAAH (0.54) | FAAHNPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL8326096 | 0.90 | L3MBTL1 (0.52) | FAAHNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL8326098 | 0.90 | L3MBTL1 (0.52) | FAAHNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL11742211 | 0.86 | SLC6A3 (0.50) | FAAHLMNAALDH1A1KMT2AKDM4E | |
| SCHEMBL11742215 | 0.86 | SLC6A3 (0.50) | FAAHLMNAALDH1A1KMT2AKDM4E | |
| SCHEMBL11741169 | 0.82 | LMNA (0.53) | FAAHNPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL11741176 | 0.82 | LMNA (0.53) | FAAHNPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL11741902 | 0.80 | MAPT (0.48) | FAAHNPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL11741909 | 0.80 | MAPT (0.48) | FAAHNPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL11739680 | 0.78 | SIGMAR1 (0.50) | NPC1RAB9ALMNAALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996014844-A1 | CYCLIC AMIDINE ANALOGS AS INHIBITORS OF NITRIC OXIDE SYNTHASE | MERCK & CO., INC. (US) | 1996-05-23 | — | — | WO | claimed |
| WO-1996014844-A1 | CYCLIC AMIDINE ANALOGS AS INHIBITORS OF NITRIC OXIDE SYNTHASE | MERCK & CO., INC. (US) | 1996-05-23 | — | — | WO | disclosed |