Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.36 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9046705 | 0.89 | GABRA1 (0.41) | GABRA1GABRG2GABRB3SOAT1LPAR1 | |
| SCHEMBL9056727 | 0.82 | GABRA1 (0.43) | GABRA1GABRG2GABRB3KCNK3KCNK9 | |
| SCHEMBL9048247 | 0.82 | GPR52 (0.40) | SMN1; SMN2LMNAHPGD | |
| SCHEMBL19289728 | 0.80 | GABRA1 (0.47) | GABRA1GABRG2GABRB3KCNK3KCNK9 | |
| SCHEMBL9045101 | 0.79 | KMT2A (0.39) | SMN1; SMN2LMNA | |
| SCHEMBL9045394 | 0.79 | AKR1B1 (0.39) | SMN1; SMN2CYP1A2CYP3A4HPGDTSHR | |
| SCHEMBL9045397 | 0.79 | GABRA1 (0.35) | GABRA1LMNATSHRGABRB2 | |
| SCHEMBL9048945 | 0.79 | GABRA1 (0.44) | GABRA1GABRG2GABRB3SOAT1LPAR1 | |
| SCHEMBL9047469 | 0.78 | CA2 (0.34) | GABRA1SMN1; SMN2CA2LMNATSHR | |
| SCHEMBL9045457 | 0.78 | GABRA1 (0.41) | GABRA1GABRG2GABRB3SOAT1LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690854-A1 | 1-PHENYL-IMIDAZOL-2-ONE BIPHENYLMETHYL COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1996-01-10 | — | — | EP | disclosed |